diff --git a/CMakeLists.txt b/CMakeLists.txt
index 2c1e4b1..21182cf 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -759,6 +759,7 @@ if(NOT UA_FORCE_CPP AND (CMAKE_COMPILER_IS_GNUCC OR "x${CMAKE_C_COMPILER_ID}" ST
 
     # Debug
     if(BUILD_TYPE_LOWER_CASE STREQUAL "debug" AND UNIX AND NOT UA_BUILD_OSS_FUZZ AND
+       UA_ENABLE_DEBUG_SANITIZER AND
        "x${CMAKE_C_COMPILER_ID}" STREQUAL "xClang" AND NOT UA_ENABLE_UNIT_TESTS_MEMCHECK)
         # Add default sanitizer settings when using clang and Debug build.
         # This allows e.g. CLion to find memory locations for SegFaults